•A therapeutic atlas of monogenic inflammatory bowel disease
•Nanomaterial-Based Strategies Targeting IL-1 Signalling in Inflammatory Bowel Disease: Therapeutic Applications and Mechanistic Insights
•Kindlin-3 is a Regulator of Force-Regulated Activation of Integrin α4β7 by CCL25 During Lymphocyte Adhesion
•Impact of inflammatory bowel disease on perioperative complications in patients undergoing surgery for metastatic spinal tumors
•Bridging preclinical and clinical efficacy of SIK2/SIK3 inhibition in inflammatory bowel disease through integrated murine, patient-derived models, and phase 2a trial-based analyses